The possibilities are endless! And it looks like Tom Holland (the actor who plays Spider-Man) feels the same way too. In an interview with CinemaBlend, Tom Holland mentioned that he would love to see the web-slinger team up with Doctor Strange.
Spider-Man and Doctor Strange previously met in Avengers: Infinity War onboard Ebony Maw’s ship. They had a quick little comedic exchange (together with Iron Man) before later teaming up with Star-Lord, Drax, Mantis and Nebula to fight Thanos on planet Titan. Just thinking about a Spidey-Doctor Strange team-up movie puts a smile on my face. Given their personalities, surely it would be a buddy comedy of sorts, with Strange functioning as the straight man next to Spidey who’s always quipping.